I'd vote with the other posters on this topic - 1) You will definitely need some sort of adjustable friction to prevent creep during flight, but you will find little to no need for in-flight adjustment. I set the friction on my Brock throttle quadrant almost 24 years ago and haven't needed to touch it since! 2) I wouldn't recommend restricting the ability to lean. Even on the ground at sea level I find that I can lean very agressively at idle, keeping the plugs and prop clean.
In terms of bumping the mixture in the air, it has been my experience that with the Brock/Rutan setup you are far more likely to nudge it rich in the process of thrashing around dealing with charts, reaching into the back for something, etc. While this seems benign, the problem is that you can potentially run for quite a while very rich, which can screw up your range if you aren't paying attention. I find my fuel flow gauge invaluable for this purpose alone (i.e., detecting abnormal fuel flow rates). Failing to lean or lean properly (or stay leaned?) has brought down at least one EZ short of an airport (probably a lot more than one). (Haven't been there or done that, thank goodness!)
If you go too lean in the air the prop stops, your heart stops, you push the mixture rich(er), the prop starts immediately and your heart eventually restarts. If you go too rich, when the prop stops you may still be short of the tie-downs... and it isn't going to restart (of course in a VariEze, you select the reserve tank and on keep truck'in, but we're not counting on that, right?). After flying with fuel flow instrumentation for a number of years I would very strongly recommend having it in the panel, it's one of my PRIMARY engine management instruments and I'd be very uncomfortable flying without it.
Blue skies,